Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub


  • ebook
  • 512
  • Bottle of Lies The Inside Story of the Generic Drug Boom
  • Katherine Eban
  • en
  • 22 May 2020
  • 9780062338808

10 thoughts on “Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub

  1. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban

    Free download Bottle of Lies The Inside Story of the Generic Drug Boom Katherine Eban Ê 2 Review Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub One of these rare books when you spend couple days or a week and will get so much information about the subject y

  2. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Rattled by revelations After giving birth by cesarean section new mothers in Uganda succumb to bacterial infections despite taking a full course of antibiotics because the uality of generic drugs exported to African countries is extremely poor to say the least Instead of the stipulated 25mg Olanzapine a Ghanai

  3. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Katherine Eban Ê 2 Review Before now I had a pretty rosy view of generic drugs I assumed they were chemically identical to the brand name drugs minus the exorbitant fees of the big pharmaceutical companies I also assumed there was an air tight system of checks in place to ensure their safety and efficacy In Katherine Eban's Bottle of Lies The Inside Story o

  4. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Katherine Eban Ê 2 Review

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub I have been studying the pharma industry for the last couple of months from the ground up and this book couldn't h

  5. says: Free download Bottle of Lies The Inside Story of the Generic Drug Boom Katherine Eban Ê 2 Review Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban

    Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub This was scary And it should be reuired reading for all adults

  6. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub

    Katherine Eban Ê 2 Review Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub After a long time I read a book that was captivating and enthralling right till the end Katherine Eban has done full justice to her years of painstaking research on the pharma industry This book has brought to light the various malpractices the pharma industry indulges in to pass the muster in FDA books and the key to US markets The book highlights the lax drug controls in developing countries like India and China to manufacture generic ve

  7. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban Katherine Eban Ê 2 Review

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Katherine Eban Ê 2 Review Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban We all need to thank Katherine Eban for her phenomenal book Bottle of Lies This is a must read book especially if you're tak

  8. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub I wish I could rate this higher because the content is super important but the writing is not great The book is about 200 pages too long and filled with clunky sentences like On the cold clear night of December 23 2002 with Christmas

  9. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban I'm pretty numb at this point to seeing instances of egregious and even obvious wrongdoing being ignored by any bodies that are capable of righting and punishing that wrongdoing But this book still dismayed and shocked cynical me I want to say that I just can't believe what is going on but I believe it This book was referred to somewhere as The Jungle of generic drugs and that characterization is spot on But whereas The Jungle spu

  10. says: Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Katherine Eban Ê 2 Review

    Bottle of Lies The Inside Story of the Generic Drug Boom E–book/E–pub Here is an important easily read current book with essential information we collectively need to prioritize rethinking of pharmaceutical ethics manufacturing delivery politics guidelines and economics worldwide I strongly encourage those interested in public health policy making regulatory affairs and global vision to he

Leave a Reply

Your email address will not be published. Required fields are marked *

Bottle of Lies The Inside Story of the Generic Drug Boom

Read & download Ü Bottle of Lies The Inside Story of the Generic Drug Boom É PDF, DOC, TXT, eBook or Kindle ePUB free Katherine Eban Ê 2 Review Free download Bottle of Lies The Inside Story of the Generic Drug Boom Mvent almost every principle of safe manufacturing to minimize cost and maximize profit confident in their ability to fool inspectors Meanwhile patients unwittingly consume medicine with unpredictable and dangerous effectsThe story of generic drugs is truly global It connects middle America to China India sub Saharan Africa and Brazil and represents the. I have been studying the pharma industry for the last couple of months from the ground up and this book couldn t have come at a better time Needless to say I bought a copy the day it was released The recent media reports over the generics price fixing scandal gave it good publicity as wellThe book is a stunning expose of the dark underbelly of the global generics industry of which India and China are the powerhouses These two countries are also the most notorious in terms of non compliance to regulations if the author is to be believed One may uestion if generics makers at other places outside of the US fare any better but that s not the point What is of foremost importance is whether the medicine we are ingesting is actually helping us get better Worse is it actually harming us insteadThe author devotes a considerable portion of the book to exposing Ranbaxy s systemic fraud that was perpetrated right from the top and continued for years first covertly and subseuently brazenly Dinesh Thakur the Indian origin American citizen who uit Bristol Myers Suibb to return and help create a global RD behemoth out of his homeland acts as the whistleblower who sought to do the right thing His years long crusade came at a great cost professionally financially and personally In a country like India it takes nerves of steel to fight a corporate behemoth with shady promoters Add to that a government and bureaucracy that prioritises India s reputation and jobs over public health In face of such hostility and threats to life most would take the easy way out and give up A case in point being Mr Nitin Mangal who merely wrote an adverse research report on an Indian real estate major and had his life nearly destroyed as a conseuenceWhile Ranbaxy hogs most of the author s attention a number of Indian pharma majors are named and shamed by describing specific shocking instances of non compliance at manufacturing plants and in some cases outright threat to the US FDA inspectors While one might want to put the blame on culture of non compliance at the lowest levels of employees and give the benefit of doubt to promoters some of whom adorn the glossy pages of business and lifestyle magazines day in and day out a statement by the chairman of a drug major on an investor call in response to the FDA s adverse report on his plant is uite telling The gentleman claims that due to a goof up on his employees part the FDA ended up inspecting the wrong plant within the premises According to him the section inspected doesn t make medicines for the US market and hence wasn t built to the FDA s standards If one chooses to believe this what this means is that it makes drugs for India and markets like Africa Latin America South East Asia etc where regulators don t give a damn Having read what this inspection exactly revealed I would never spend a penny on his company s medicine But then from what I understand most Indian companies use their non FDA compliant plants to make drugs for the Indian market Go figureMulti tier manufacturing systems in the industry are not even a secret I have interacted with a pharma company that stated this as a matter of fact and at the time I didn t know enough of the industry to be horrified You manufacture the worst uality a market will tolerate plain and simple The world markets are a tiered system in the minds of pharma companies The absolute rejects and trashworthy stuff ends up in poor African countries where there are practically no checks and balances one reason why there are much lesser rejects in Indian pharma plants as against globally and the best one can produce goes to the US and EU The FDA doesn t come out looking good either On the one hand it faces practical challenges in conducting inspections overseas at faraway and remotely located plants with hardly any inspectors keen on going There is the additional reuirement of obtaining visas which necessitates informing the companies much in advance and allowing them all the time reuired for a cover up in the US the FDA conducts inspections without notice and with higher freuency On the other when enterprising inspectors uality approach and integrity of inspectors can be uite variable uncover blatant fraud and manipulation at these facilities it seeks to kill the messenger instead Political pressure to approve generics faster in order to reduce healthcare costs and the agency s own budget being made contingent on success in granting approvals has set up the system to fail Add to that the slow moving nature of a bureaucracy and what you get is a paper tiger and a convenient scapegoat on which to pin blame for public health disasters from sub standard medicine In the Ranbaxy case while one arm of the FDA was investigating outright fraud the other kept granting approvals to new medicines by the company despite being confident that the underlying data was most certainly fakeIndian companies have taken full advantage of this and ended up getting caught despite Nevertheless with Indian political and regulatory backing the pharma lobby has managed to use the US desire to have access to cheap drugs to water down the process The FDA conducted surprise inspections for a while but it was given a uiet burial with no explanation offered In return the industry has merely promised to reform itself and claimed that it takes time to institute a culture of compliance in a country used to the chalta hai attitude While this may be true in part I believe it has to do with concern for the bottom line uality comes at a cost and that lowers margins With the product by nature supposed to be cheap and currently facing stiff price competition in the US I doubt things are going to change for the better anytime soon As for the Indian market we were always second class citizens anyways I doubt it can get any worse The only loser in the whole game is the patient who doesn t know whether he is ingesting elixir or poison much the worse if for a chronic condition

Read ç PDF, DOC, TXT, eBook or Kindle ePUB free Ê Katherine Eban

Read & download Ü Bottle of Lies The Inside Story of the Generic Drug Boom É PDF, DOC, TXT, eBook or Kindle ePUB free Katherine Eban Ê 2 Review Free download Bottle of Lies The Inside Story of the Generic Drug Boom Katherine Eban’s Bottle of Lies exposes the deceit behind generic drug manufacturing and the attendant risks for global health Drawing on exclusive accounts from whistleblowers and regulators as well as thousands of pages of confidential FDA documents Eban reveals an industry where fraud is rampant companies routinely falsify data and executives circu. Rattled by revelations After giving birth by cesarean section new mothers in Uganda succumb to bacterial infections despite taking a full course of antibiotics because the uality of generic drugs exported to African countries is extremely poor to say the least Instead of the stipulated 25mg Olanzapine a Ghanaian psychiatrist gave 10mg of the same drug to one of his patients with psychosis and saw no results It s shocking that doctors throughout Africa have to adjust their medical treatment sometimes doubling or tripling recommended doses to produce a therapeutic effect Katherine Eban explains that while the goal of a branded drug company is to make the best possible drugs to be sold at highest possible price that of generic drug companies is to make the best cures affordable and available to all To make profit many generic drug companies mess with the uantity of active ingredients compromise on sterility cut down on clinical trials fabricate raw data Bottle of Lies opened as an expose on the poor uality of some genric drugs imported to the USA loosely based on Dinesh Thakur s experience in Ranbaxy went on to reveal the dark side of pharmaceutical companies like Pliva Dr Reddy s Glenmark Ethex Zydnus and Sandoz Consumers from developing and underdeveloped countries who re being sold bottles with bigger lies printed on them are continuing victims of uality slip ups that endanger lives Bottle of Lies is a shocking read and an eye opener It has made me careful about the drugs I prescribe and consume

Free download Bottle of Lies The Inside Story of the Generic Drug Boom

Read & download Ü Bottle of Lies The Inside Story of the Generic Drug Boom É PDF, DOC, TXT, eBook or Kindle ePUB free Katherine Eban Ê 2 Review Free download Bottle of Lies The Inside Story of the Generic Drug Boom Ultimate litmus test of globalization what are the risks of moving drug manufacturing offshore and are they worth the savings A decade long investigation with international sweep high stakes brinkmanship and big money at its core Bottle of Lies reveals how the world’s greatest public health innovation has become one of its most astonishing swindles?. I m pretty numb at this point to seeing instances of egregious and even obvious wrongdoing being ignored by any bodies that are capable of righting and punishing that wrongdoing But this book still dismayed and shocked cynical me I want to say that I just can t believe what is going on but I believe it This book was referred to somewhere as The Jungle of generic drugs and that characterization is spot on But whereas The Jungle spurred the creation of the FDA and food regulations in general this book highlights how the FDA utterly fails us with high level bureaucrats overturning decisions to shut down or restrict imports of contaminated and ineffective drugs due to political considerations the desire for low cost drugs or to remedy shortages of certain drugs But what good is it to have a drug available if it may kill you or be utterly ineffective I m just dismayed that this is allowed to continue This certainly makes me want to do everything I can to avoid taking any generic drugs and to not allow my family to do so I had always believed they were the euivalent of the name brand drugs It seems to me that it should be without uestion that no one has an inherent right to sell drugs in the US There is no reason that the FDA must grant approval for a particular company to sell drugs or food for that matter in our market Our government s priority should be to keep its citizens safe So just because it is difficult to inspect a foreign manufacturing plant is no reason that we should essentially forego inspections or do them in such a way that they are useless or even worse ignore wrongdoing and outright fraud when we find it We could make the companies bear those costs We should set up offices that allow for proper inspections And we should not allow companies that sell ineffective and tainted drugs in our market That should be a given The fact that it is not is just outrageous and astounding One important point that the book makes but is not a main focus is that it is ultimately in everyone s self interest to make sure that ineffective drugs are not widely manufactured and used Even if we took the position that the only people who mattered were Americans and we created and maintained a system that every drug exported for sale within the US needed to meet top bioeuivilancy sterility and purity standards but ignore and allow inferior drugs to go to other countries that adds to the problem of the emergence of drug resistant strains of various pathogens and once those show up they don t care where you live or how much money you have They can infect anyone This is a book everyone could read because if everyone knew about this issue there would be real outrage and it could force our government to at least take some action